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Inducible CRISPR-Cas9 improves the precision of genome editing in rice

September 19th, 2019 / ISAAA, US

DNA delivery into tissue cultures is a simple method for expressing CRISPR-Cas9 and creating genome edits in the plants. This approach, however, allows strong doses of CRISPR-Cas9 to persist far beyond the incidence of targeting i.e. until genetic segregation of the Cas9 gene.

Although precision is an inherent quality of CRISPR-Cas9, the strong persistent doses in numerous cells throughout the …

New technologies show better details on GM plants

January 23rd, 2019 / ISAAA, US

Researchers from the Salk Institute used the latest DNAsequencing technologies to study exactly what happens at a molecular level when new genes are inserted into plants. Scientists usually rely on Agrobacterium tumefaciens when they want to put a new gene into a plant. Decades ago, scientists discovered that when the bacteria infected a tree, it …

Genetically engineered microbes make their own fertiliser

April 11th, 2017 / Science, US

Industrial fertilizers help feed billions of people every year, but they remain beyond the reach of many of the world’s poorest farmers. Now, researchers have engineered microbes that, when added to soil, make fertilizer on demand, producing plants that grow 1.5 times larger than crops not exposed to the bugs …

Health care, energy & food all could be transformed by synthetic biology

February 8th, 2017 / Genetic Literacy Project, US

Synthetic biology builds upon genetic engineering—something that has been around for 30 years and the results of which are everywhere in our daily lives…Genetic engineering adds new DNA to an organism, and synthetic biology is similar. The end goal of both is to edit the DNA code of an organism …

What everyone should know about cut-and-paste genetics

December 1st, 2015 / Nature, UK

The ethics of human-genome editing is in the spotlight again as a large international meeting on the topic is poised to kick off in Washington DC. Ahead of the summit, which is being jointly organized by the US National Academy of Sciences, the US National Academy of Medicine, the …